This is an inter-disciplinary course that integrates concepts from mathematics, physics, engineering and computer science to educate students on the design of intelligent spacecraft. Course instruction takes a new tact best summarized by the expression: All science was new at some point. This approach augments class topics with historic context and, in some cases, facsimiles of original works such as Galileo's theory on planetary motion. Course topics include mathematical models of planetary motion and heat transfer and how these models are used in designing intelligent spacecraft, i.e., robotic systems which can autonomously perform complex space-mission tasks.